Protective Mechanisms of Prenatal Aspirin Therapy on Maternal Vascular Dysfunction Following Preeclampsia

Inclusion:
*  18 years or older,
*  12 weeks to 5 years postpartum
*  and one of the following: 1. women who had a normal pregnancy and did not use low does aspirin (LDA) during pregnancy, 2. women who had a normal pregnancy and used LDA during pregnancy, 3. women who had preeclampsia and did not use LDA during pregnancy, 4. women who had preeclampsia and used LDA during pregnancy. Exclusion:
*  current daily aspirin use,
*  skin diseases,
*  current tobacco use,
*  diagnosed or suspected hepatic or metabolic disease including chronic kidney disease (CKD) defined as reduced eGFR \< 60 mL/min/1.73m2,
*  statin or other cholesterol-lowering medication,
*  current antihypertensive medication,
*  history of hypertension prior to pregnancy,
*  history of gestational diabetes,
*  current pregnancy,
*  body mass index \<18.5 kg/m2,
*  allergy to materials used during the experiment.(e.g. latex),
*  known allergies to study drugs.