ICONIC-ASCEND

Dermatology Immunology Skin and Dermatologic Pediatric Subjects Adult Subjects

The main purpose of this study is to assess how well JNJ-77242113 works when compared to placebo and ustekinumab in participants with moderate to severe plaque psoriasis.

Novartis CYTB323K12201; CAR-T for Scleroderma

Internal Medicine Immunology Skin and Dermatologic Adult Subjects

The purpose of this study is to evaluate the efficacy, safety and tolerability of rapcabtagene autoleucel (administered once following lymphodepletion) in participants with severe refractory diffuse cutaneous systemic sclerosis relative to rituximab.