Studies
Blood Based Biomarkers For Minimal Residual Disease Detection in Pediatric Sarcomas
Cancer
Pediatrics
Pediatric Subjects
Adult Subjects
Specimen Banking With Clinical and Genomic Data Registry With the Establishment of Tumor Models for Pediatric Cancers
Cancer
Pediatrics
Pediatric Subjects
Adult Subjects
MK-9999-U01 Master Protocol: A Phase 1/2 Platform Study to Evaluate the Safety and Efficacy of Investigational Agents in Pediatric and Young Adult Participants with Hematologic Malignancies or Solid Tumors
Cancer
Pediatrics
Leukemia
Lymphoma
Sarcoma
Brain and Spinal Cord Cancer
Pediatric Subjects
Adult Subjects
Substudy 01A is part of a platform study. The purpose of this study is to assess the efficacy and safety of zilovertamab vedotin in pediatric participants with relapsed or refractory B-cell acute lymphoblastic leukemia (B-ALL), diffuse large B-cell lymphoma (DLBCL)/Burkitt lymphoma, or neuroblastoma and in pediatric and young adult participants with Ewing sarcoma.
Lurbinectedin in FET-Fused Tumors
Cancer
Pediatrics
Leukemia
Sarcoma
Pediatric Subjects
Adult Subjects
The purpose of this study is to find out if a drug called lurbinectedin (the "study drug") is safe and effective at treating people with recurrent or relapsed solid tumors, including Ewing sarcoma.