Studies

Targeting Myeloid-Derived Suppressor Cells in Patients with Recurrent/Progressive Grade 4 Glioma: Phase 1 Trial of Sitagliptin

Cancer Brain and Spinal Cord Cancer Adult Subjects Female Subjects Male Subjects

Sitagliptin, when combined with standard-of-care drug bevacizumab, is being tested to 1) find out if it is effective at treating gliomas that have returned or progressed after treatment, and 2) find out what the highest dose of sitagliptin is appropriate to give when combined with bevacizumab.