Anjali Sharathkumar | University of Iowa Clinical Research and Trials

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Studies

ATHN 10: Rare Coagulation Disorders

Pediatrics Pediatric Subjects Adult Subjects

A phase 1b, open-label, multicenter study of Mavorixafor in patients with severe congenital neutropenia and chronic neutropenia disorders

Pediatrics Pediatric Subjects Adult Subjects

This is a 2-part study of mavorixafor in participants diagnosed with chronic neutropenia. The main goal of Part 1 (Phase 1b) is to help researchers learn more about how the investigational medicine, mavorixafor, impacts people living with chronic neutropenia (including congenital, idiopathic, and cyclic). In Part 2 (Phase 2), the safety and tolerability of chronic dosing of mavorixafor will be evaluated in a larger participant population and the impact of 6-month chronic dosing of mavorixafor on participant neutropenia.