Douglas Hornick | University of Iowa Clinical Research and Trials

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Studies

MKC-CI-002, MNKD-101, Pulmonary Nontuberculous

Internal Medicine Pulmonology Lung Disease Adult Subjects

This clinical trial is designed to compare the efficacy and safety of Clofazimine Inhalation Suspension versus placebo when added to guideline-based therapy (GBT)

SPR720-202, SPR720, for MAC Pulmonary Disease

Internal Medicine Pulmonology Lung Disease Adult Subjects

The purpose of the study is to evaluate

1. The microbiological response and clinical efficacy of SPR720 compared with placebo in participants with nontuberculous mycobacteria pulmonary disease (NTM-PD).
2. The safety and tolerability of SPR720 in a participants population with NTM- PD
3. The pharmacokinetic (PK) of SPR719, active moiety, following orally (po) administered prodrug SPR720 in a participant population with NTM-PD.