Michael Goodheart | University of Iowa Clinical Research and Trials

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Studies

HCCC-A PHASE 1 DOSE FINDING, SAFETY, AND PRELIMINARY CLINICAL ACTIVITY STUDY OF VT-101 IN ADVANCED OVARIAN CANCER

Cancer Gynecology Ovarian Cancer Electrophysiology Adult Subjects Female Subjects

This Phase 1, open-label study will evaluate VT-101, an investigational small-molecule therapy, in adult women with advanced, recurrent, or relapsed epithelial ovarian cancer. The primary objectives are to assess the safety, tolerability, and pharmacokinetic profile of VT-101 and to identify a recommended dose for further study. Secondary and exploratory objectives include evaluation of preliminary antitumor activity and characterization of treatment-related effects in participants with limited standard treatment options.