Skin Cancer | University of Iowa Clinical Research and Trials

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Phase 3 Pembrolizumab Study for Squamous Cell Carcinoma

Cancer Internal Medicine Skin Cancer Adult Subjects Female Subjects Male Subjects

This is a randomized, double-blind, study that compares pembrolizumab (MK-3475) with placebo given as adjuvant therapy in participants with high-risk locally advanced cutaneous squamous cell carcinoma (LA cSCC) that have undergone surgery with curative intent in combination with radiotherapy. The primary hypothesis is that pembrolizumab is superior to placebo in increasing recurrence free survival (RFS).