Studies

80202135SJS3001, Nipocalimab, SjD

Internal Medicine Adult Subjects

The purpose of this study is to evaluate the clinical efficacy and safety of nipocalimab in participants with moderate to severe Sjogren's disease (SjD).

CLN-978-SL-101; CLN-978 for SLE

Internal Medicine Immunology Autoimmune Adult Subjects

Phase 1b, open-label study of CLN-978 administered subcutaneously in patients with Moderate to Severe Systemic Lupus Erythematosus (SLE).

Novartis CYTB323L12201; CAR-T for myositis

Internal Medicine Adult Subjects

A Phase 2, randomized, open-label, controlled study to evaluate the efficacy and safety of rapcabtagene autoleucel versus comparator in participants with severe refractory idiopathic inflammatory myopathies (IIM)

Novartis CYTB323J12201; CAR-T for SLE with LN

Internal Medicine Immunology Nephrology Autoimmune Kidney Disease Adult Subjects

The purpose of this study is to evaluate the efficacy and safety of rapcabtagene autoleucel (administered once following lymphodepletion) versus Standard of Care (SOC) in patients with systemic lupus erythematosus (SLE) with active, refractory lupus nephritis (LN).

CAIN457C22301, Secukinumab for PMR

Internal Medicine Adult Subjects

The purpose of this study is to demonstrate the efficacy and safety of secukinumab 300 milligram (mg) and 150 mg administered subcutaneously (s.c.) for 52 weeks in combination with prednisone tapered over 24 weeks in adult participants with PMR who have recently relapsed.

CAIN457R12301 for Giant Cell Arteritis

Internal Medicine Adult Subjects

This is a phase III study of efficacy and safety of secukinumab versus placebo, in combination with glucocorticoid taper regimen, in patients with giant cell arteritis (GCA)